Gene therapy
Gene therapy is the use of nucleic acid polymers as a drug to treat disease by therapeutic delivery into a patient's cells, where they are either expressed as proteins, interfere with the expression o...
Gene therapy - Wikipedia
Cancer cure: Promising new gene therapy drug reprograms immune cells to kill cancer
SILVER SPRING, MARYLAND— A panel of experts advising the U.S. Food and Drug Administration has unanimously recommended the approval of a new cancer drug from pharmaceutical giant Novartis. The drug wo...
First Human Treated With CRISPR Gene-Edited Cells In China, Report Says
For the first time, a cancer patient is being treated with cells altered using a gene editing technique called CRISPR-Cas9.
CRISPR: Gene Editing Is Just The Beginning
The real power of the biological tool lies in exploring how genomes work. Molecular biologists are riding a wave of new technologies made possible by CRISPR.
Scientists Claim They've Completed The First Successful Gene Therapy Against Human Ageing
The CEO of Bioviva USA Inc , Elizabeth Parrish, claims to be the first human in world history to have successfully reversed the effects of natural ageing - thanks to experimental gene therapy provided...
U.K. Regulator Gives Go-Ahead For Scientists To Edit Genes In Human Embryos
A team of British scientists received approval by U.K.'s fertility regulator to edit genes in human embryos. "It is the first time a country has considered the DNA-altering technique in embryos and ap...
Suicide Gene Therapy Kills Prostate Tumor Cells
Results from a long-term clinical trial conducted by cancer researchers at Houston Methodist Hospital show that combining radiation treatment with 'suicide gene therapy' provides a safe and effective ...
The Quest To Make CRISPR Even More Precise
To fulfill its revolutionary promise, the gene-editing technique will need to be edited. More than ever, we can view the genomes of humans and other organisms as drafts—not final and canonical texts, ...
World's first baby battling leukaemia is saved by gene modification treatment
A British baby has become the first person in the world to be given a miracle treatment for cancer. Little Layla Richards had one of the worst cases of leukaemia her doctors had ever seen and, when al...
Researchers Find Variation In Gene For Brain-Derived Neurotropic Factor Which Could Impact Obesity
A team of researchers claims that they have found variation in a gene for brain-derived neurotropic factor (BDNF), which could have an impact on obesity among adults and children. The study researcher...
In CRISPR Advance, Scientists Successfully Edit Human T Cells
In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9. Because th...
Bad Genes Lead Teens To Binge-Eating
Binge-eating in teenagers may be linked to a gene variation, according to new research from the University of Queensland. The UQ Diamantina Institute’s Professor David Evans and a University College L...
Gene Therapy Restores Hearing In Deaf Mice
Using gene therapy, researchers at Boston Children's Hospital and Harvard Medical School have restored hearing in mice with a genetic form of deafness. Their work, published online July 8 by the journ...
Massachusetts General Research Team Evolves CRISPR-Cas9 Nucleases With Novel Properties
A team of Massachusetts General Hospital researchers has found a way to expand the use and precision of the powerful gene-editing tools called CRISPR-Cas9 RNA-guided nucleases. In their report receivi...
UPDATED: A Gene Therapy 'Cure' For Blindness Starts To Fade Within A Few Years
The two key reasons why gene therapies command such avid attention these days center on their promise of providing a cure for some terrible conditions along with the prospect of a 7-figure price tag. ...
Vectors in gene therapy
Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes...
Viral vector
Viral vectors are a tool commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism (in vivo) or in cell culture (in vitro). V...
Viral vector - Wikipedia
Adeno associated virus and gene therapy of the human retina
Retinal gene therapy holds great promise in treating different forms of non-inherited and inherited blindness.In 2008, three independent research groups reported that patients with the rare genetic re...
What Does the Future of Biotechnology Therapies Look Like?
Biotechnology is still a relatively new field with great potential for driving medical progress. Much of that progress is likely to result from advances in personalized medicine. This new treatment pa...
Gene Therapy: 'Tame HIV' Used To Cure Disease
The lives of six boys with a deadly genetic disease have been transformed by a pioneering treatment to correct errors in their DNA, say doctors. A defective immune system in Wiskott-Aldrich syndrome l...
Adenovirus
Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA ...
Adenovirus - Wikipedia
Gene therapy - A Breakthrough Against Leukemia Using Altered T-Cells
Emma Whitehead, 7, has been in full remission for months after scientists used a disabled form of H.I.V. to reprogram her immune system to kill cancer cells.
Scientists Discover Key Driver Of Human Aging: May Lead To Slowing Or Reversing Aging Process
In the study, scientists at the Salk Institute and the Chinese Academy of Science found that the genetic mutations underlying Werner syndrome, a disorder that leads to premature aging and death, resul...
Gene therapy creates biological pacemaker
Pig-heart cells modified to keep a steady beat. Gene therapy could soon join the electronic pacemaker as a treatment for a weak heart. By inserting a specific gene into heart-muscle cells, researchers...
Chinese Scientists Genetically Modify Human Embryos For The First Time
In a world first, Chinese scientists have reported editing the genomes of human embryos. The results are published1 in the online journal Protein & Cell and confirm widespread rumours that such experi...
Newly-Found T Memory Stem Cells May Be Key to Gene Therapy
Genetically engineered T memory stem cells (Tscm) can last more than 12 years in patients’ bodies, and can continually generate appropriate T cell armies for them, says an innovative study looking at ...
Gene therapy for color blindness
Gene therapy for color blindness is an experimental gene therapy aiming to convert congenitally colorblind individuals to trichromats by introducing a photopigment gene that they lack. Though partial...