Noncoding DNA
In genomics and related disciplines, noncoding DNA sequences are components of an organism's DNA that do not encode protein sequences. Some noncoding DNA is transcribed into functional non-coding RNA ...
How Genes are Regulated: Transcription Factors - YouTube
Like us on Facebook: https://www.facebook.com/pages/Stroma-Studios/290868104261105?sk=wall Each cell in our body inherits the same master copy of DNA, but di...
Regulation of gene expression
Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gen...
Regulation of gene expression - Wikipedia
Transcription factor
In molecular biology and genetics, a transcription factor (sometimes called a sequence-specific DNA-binding factor) is a protein that binds to specific DNA sequences, thereby controlling the rate of t...
Transcription factor - Wikipedia
Operator (biology)
In genetics, an operator is a segment of DNA to which a transcription factor binds to regulate gene expression. The transcription factor is typically a repressor, which can bind to the operator to pre...
Operator (biology) - Wikipedia
Enhancer (genetics)
In genetics, an enhancer is a short (50-1500 bp) region of DNA that can be bound with proteins (activators) to activate transcription of a gene or genes. These proteins are usually referred to as tran...
Promoter (biology)
In genetics, a promoter is a region of DNA that initiates transcription of a particular gene. Promoters are located near the transcription start sites of genes, on the same strand and upstream on the ...
Promoter (biology) - Wikipedia
Basic helix-loop-helix leucine zipper transcription factors
Basic helix-loop-helix leucine zipper transcription factors are, as their name indicates, transcription factors containing both Basic helix-loop-helix and leucine zipper motifs.An example is Microphth...
ZNF638
Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. ...
ATF1
Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene.This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZI...
ATF1 - Wikipedia
MLL3
Histone-lysine N-methyltransferase MLL3 is an enzyme that in humans is encoded by the MLL3 gene.This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nucle...
MLL3 - Wikipedia
ARID1A
AT-rich interactive domain-containing protein 1A is a protein that in humans is encoded by the ARID1A gene.
ARID1A is a member of the SWI/SNF family, whose members have helicase and ATPase activit...
ARID1A - Wikipedia
Core binding factor
The Core binding factor (CBF) is a group of heterodimeric transcription factors. Core binding factors are composed of:
MTA1
Metastasis-associated protein MTA1 is a protein that in humans is encoded by the MTA1 gene.
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, spe...
MTA1 - Wikipedia
ZBTB40
Zinc finger and BTB domain-containing protein 40 is a protein that in humans is encoded by the ZBTB40 gene.
ZBTB40 - Wikipedia
BBX (gene)
HMG box transcription factor BBX also known as bobby sox homolog or HMG box-containing protein 2 is a protein that in humans is encoded by the BBX gene.
Model organisms have been used in the stud...
BLZF1
Golgin-45 is a protein that in humans is encoded by the BLZF1 gene.
BLZF1 has been shown to interact with GORASP2.
BLZF1 - Wikipedia
Winged-helix transcription factors
Consisting of about 110 amino acids, the domain in winged-helix transcription factors has four helices and a two-strand beta-sheet. These proteins are classified into 19 families called FoxA-FoxS. M...
HOXC13
Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcripti...
HOXC13 - Wikipedia
HOXB2
Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It ...
HOXB2 - Wikipedia
Myf5
Myogenic factor 5 is a protein that in humans is encoded by the MYF5 gene.It is a protein with a key role in regulating muscle differentiation or myogenesis. Without Myf5 and MyoD, myogenic cells will...
ZNF24
Zinc finger protein 24 is a protein that in humans is encoded by the ZNF24 gene.
ZNF24 - Wikipedia
P53
Tumor proteins p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), are encoded...
P53 - Wikipedia
JUNB
Transcription factor jun-B is a protein that in humans is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary grow...
JUNB - Wikipedia
TSC22D1
TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene.TSC22 encodes a transcription factor and belongs to the large family of early response genes.TSC22D1 forms homo...
TSC22D1 - Wikipedia
ZNF219
Zinc finger protein 219 is a protein that in humans is encoded by the ZNF219 gene.
ZNF219 - Wikipedia
SALL1
Sal-like 1 (Drosophila), also known as SALL1, is a protein which in humans is encoded by the SALL1 gene. As the full name suggests, it is one of the human versions of the spalt (sal) gene known in Dro...
SALL1 - Wikipedia
E2F
E2F is a group of genes that codifies a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as suppressors: E2F3b, E2F4-8. All of...
E2F - Wikipedia
ISL1
Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the ISL1 gene.
This gene encodes a transcription factor containing two N-terminal LIM domains and one C-terminal homeo...
ISL1 - Wikipedia
MXI1
MAX-interacting protein 1 is a protein that in humans is encoded by the MXI1 gene.
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal ce...
MXI1 - Wikipedia
Therapeutic gene modulation
Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that ge...
Therapeutic gene modulation - Wikipedia