Smoking And Heavy Alcohol Use Are Associated With Epigenetic Signs Of Aging
Using data from the publicly available Gene Expression Omnibus, Robert A. Philibert, MD, PhD and colleagues at the University of Iow8a and other institutions analyzed patterns of DNA methylation, a mo...
Relaxed DNA may contribute to aging
Study finds clues to senescence in cells given rare aging disorder. People with Werner syndrome—a rare disease with symptoms that mimic premature aging—usually go gray in their 20s, develop cataracts ...
Caffeine + alcohol keeps your chromosomes just right
The ends of your chromosomes are sensitive to a variety of environmental factors.
DNA damage theory of aging - "Frankenstein" Bog Mummies Discovered in Scotland
Two Bronze Age bodies found on a Scottish island are actually made from six people, a new study reveals. ... A cynical theory, study author Brown said, assumes that the Bronze ...
Smoking And Heavy Alcohol Use Are Associated With Epigenetic Signs Of Aging
Using data from the publicly available Gene Expression Omnibus, Robert A. Philibert, MD, PhD and colleagues at the University of Iow8a and other institutions analyzed patterns of DNA methylation, a mo...
Telomere
A telomere is a region of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighbouring chromosomes. Its name...
Telomere - Wikipedia
Selectivity theory (aging)
Ageing (British English) or aging (American English) is the process of becoming older. It represents the accumulation of changes in a person over time. In humans, ageing refers to a multidimensional p...
Selectivity theory (aging) - Wikipedia
Cerebroretinal microangiopathy with calcifications and cysts
Cerebroretinal microangiopathy with calcifications and cysts (CRMCC) is a rare genetic disorder, which affects multiple organs. Its hallmarks are widespread progressive calcifications, cysts and abnor...
Cerebroretinal microangiopathy with calcifications and cysts - Wikipedia
Mir-598 microRNA precursor family
In molecular biology mir-598 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
miR-598 has been shown to directly target ...
Mir-598 microRNA precursor family - Wikipedia
DNA damage theory of aging
The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal struc...
Kinase binding protein CGI-121
In molecular biology, the kinase binding protein CGI-121 family of proteins includes the kinase binding protein CGI-121 and its homologues. CGI-121 has been shown to bind to the p53-related protein ki...
Kinase binding protein CGI-121 - Wikipedia
ACD (gene)
Adrenocortical dysplasia protein homolog is a protein that in humans is encoded by the ACD gene.
This gene encodes a protein that is involved in telomere function. This protein is one of six core ...
ACD (gene) - Wikipedia
JTB (gene)
Protein JTB, also known as the jumping translocation breakpoint protein or prostate androgen-regulated protein (PAR), is a protein that in humans is encoded by the JTB gene.The JTB family of proteins ...
JTB (gene) - Wikipedia
RIF1
Telomere-associated protein RIF1 is a protein that in humans is encoded by the RIF1 gene.RIF1 and RIF2 cap the chromosome ends (telomeres).
RIF1 - Wikipedia
Senescence
Senescence (/sɪˈnɛsəns/) (from Latin: senescere, meaning "to grow old", from senex) or biological aging (also spelled biological ageing) is the gradual deterioration of function characteristic of ...
Senescence - Wikipedia
Neuroendocrine theory of aging
Senescence (/sɪˈnɛsəns/) (from Latin: senescere, meaning "to grow old", from senex) or biological aging (also spelled biological ageing) is the gradual deterioration of function characteristic of ...
Stem cell theory of aging
The stem cell theory of aging is a new theory which was recently formulated by several scientists and which postulates that the aging process is the result of the inability of various types of stem ce...
Telomestatin
Telomestatin is a macrocyclic chemical compound that acts by inhibiting the telomerase activity of the cancer cells. It was first isolated from the bacteria Streptomyces anulatus. Telomestatin induce...
Telomestatin - Wikipedia
Order to disorder theory of aging
Senescence (/sɪˈnɛsəns/) (from Latin: senescere, meaning "to grow old", from senex) or biological aging (also spelled biological ageing) is the gradual deterioration of function characteristic of ...
Order to disorder theory of aging - Wikipedia
POT1
Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene.
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenan...
POT1 - Wikipedia
Network theory of aging
The network theory of aging supports the idea that multiple connected processes contribute to the biology of aging. Kirkwood and Kowald helped to establish the first model of this kind by connecting t...