RNA world hypothesis
The RNA world hypothesis proposes that self-replicating ribonucleic acid (RNA) molecules were precursors to all current life on Earth. It is generally accepted that current life on Earth descends from...
RNA world hypothesis - Wikipedia
Scientists Find Evidence for Alternate Theory of How Life Arose
A new study led by scientists at The Scripps Research Institute (TSRI) offers a twist on a popular theory for how life on Earth began about...
A Newly Made RNA Strand Bolsters Ideas About How Life On Earth Began
RNA molecule is able to synthesize other RNAs, a feat believed central to the origin of life
RNA
Ribonucleic acid (RNA) is a polymeric molecule. It is implicated in various biological roles in coding, decoding, regulation, and expression of genes. DNA and RNA are nucleic acids, and, along with pr...
RNA - Wikipedia
Ribozyme
Ribozymes (ribonucleic acid enzymes), also termed catalytic RNA, are RNA molecules that are capable of catalyzing specific biochemical reactions, similar to the action of protein enzymes. The 1982 dis...
Ribozyme - Wikipedia
Riboswitch
In molecular biology, a riboswitch is a regulatory segment of a messenger RNA molecule that binds a small molecule, resulting in a change in production of the proteins encoded by the mRNA. Thus, an m...
Riboswitch - Wikipedia
Purine riboswitch
A purine riboswitch is a sequence of ribonucleotides in certain messenger RNA (mRNA) that selectively binds to purine ligands via a natural aptamer domain. This binding causes a conformational change...
Purine riboswitch - Wikipedia
Cobalamin riboswitch
Cobalamin riboswitch is a cis-regulatory element which is widely distributed in 5' untranslated regions of vitamin B12 (Colbalamin) related genes in bacteria. Riboswitches are metabolite binding domai...
Cobalamin riboswitch - Wikipedia
TPP riboswitch
The TPP riboswitch, also known as the THI element and Thi-box riboswitch, is a highly conserved RNA secondary structure. It serves as a riboswitch that binds directly to thiamine pyrophosphate (TPP) ...
TPP riboswitch - Wikipedia
Lysine riboswitch
The Lysine riboswitch is a metabolite binding RNA element found within certain messenger RNAs that serve as a precision sensor for the amino acid lysine. Allosteric rearrangement of mRNA structure is ...
Lysine riboswitch - Wikipedia
FMN riboswitch
The FMN riboswitch (also known as RFN element) is a highly conserved RNA element that is found frequently in the 5'-untranslated regions of prokaryotic mRNAs that encode for flavin mononucleotide (FMN...
FMN riboswitch - Wikipedia
Vg1 ribozyme
The Vg1 ribozyme is a manganese dependent RNA enzyme or ribozyme which is the smallest ribozyme to be identified. It was identified in the 3' UTR of Xenopus Vg1 mRNA transcripts and mouse beta-actin m...
Vg1 ribozyme - Wikipedia
AdoCbl riboswitch
Cobalamin riboswitch is a cis-regulatory element which is widely distributed in 5' untranslated regions of vitamin B12 (Colbalamin) related genes in bacteria. Riboswitches are metabolite binding domai...
AdoCbl riboswitch - Wikipedia
RNase MRP
RNase MRP (also called RMRP) is an enzymatically active ribonucleoprotein with two distinct roles in eukaryotes. In mitochondria it plays a direct role in the initiation of mitochondrial DNA replicat...
RNase MRP - Wikipedia
Cyclic di-GMP-II riboswitch
Cyclic di-GMP-II riboswitches (also c-di-GMP-II riboswitches) form a class of riboswitches that specifically bind cyclic di-GMP, a second messenger used in multiple bacterial processes such as virulen...
Cyclic di-GMP-II riboswitch - Wikipedia
Database for bacterial group II introns
The Database for Bacterial Group II Introns is a repository of full-length, non-redundant group II introns present in bacterial DNA sequence.
YkoK leader
The Ykok leader or M-box is a Mg-sensing RNA structure that controls the expression of Magnesium ion transport proteins in bacteria. It is a distinct structure to the Magnesium responsive RNA elemen...
YkoK leader - Wikipedia
Hairpin ribozyme
The hairpin ribozyme is a small section of RNA that can act as an enzyme known as a ribozyme. Like the hammerhead ribozyme it is found in RNA satellites of plant viruses. It was first identified in th...
Hairpin ribozyme - Wikipedia
SAM-II riboswitch
The SAM-II riboswitch is a RNA element found predominantly in alpha-proteobacteria that binds S-adenosyl methionine (SAM). Its structure and sequence appear to be unrelated to the SAM riboswitch found...
SAM-II riboswitch - Wikipedia
Moco RNA motif
The Moco RNA motif is a conserved RNA structure that is presumed to be a riboswitch that binds molybdenum cofactor or the related tungsten cofactor. Genetic experiments support the hypothesis that t...
Moco RNA motif - Wikipedia
Hepatitis delta virus ribozyme
The hepatitis delta virus (HDV) ribozyme is a non-coding RNA found in the hepatitis delta virus that is necessary for viral replication and is thought to be the only catalytic RNA known to be required...
Hepatitis delta virus ribozyme - Wikipedia
Ribosome Nascent chain Complex
Ribosome-nascent chain complex (RNC) refers to the collection of molecules that constitute a ribosome attached to the polypeptide (protein) that it is synthesising. The synthesis of the nascent polype...
Ribosome Nascent chain Complex - Wikipedia
GlmS glucosamine-6-phosphate activated ribozyme
The Glucosamine-6-phosphate activated ribozyme ( glmS ribozyme) is an RNA structure that is both a ribozyme, since it catalyzes a chemical reaction, and a riboswitch, since it regulates genes in respo...
GlmS glucosamine-6-phosphate activated ribozyme - Wikipedia
Tetrahydrofolate riboswitch
Tetrahydrofolate riboswitches are a class of homologous RNAs in certain bacteria that bind tetrahydrofolate (THF). It is almost exclusively located in the probable 5' untranslated regions of protein-...
Tetrahydrofolate riboswitch - Wikipedia
Leadzyme
Leadzyme is a small ribozyme (catalytic RNA), which catalyzes the cleavage of a specific phosphodiester bond. It was discovered using an in-vitro evolution study where the researchers were selecting f...
Group II intron
Group II introns are a large class of self-catalytic ribozymes as well as mobile genetic element found within the genes of all three domains of life. Ribozyme activity (e.g., Self-splicing) can occur ...
Group II intron - Wikipedia
Mesoplasma florum riboswitch
Riboswitches are cis-acting regulatory elements located within the 5’UTR of mRNA transcripts. These regulatory elements bind small molecules which results in a conformational change within the 5’UTR o...
Mesoplasma florum riboswitch - Wikipedia
SAM-SAH riboswitch
The SAM-SAH riboswitch is a conserved RNA structure in certain bacteria that binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) and is therefore presumed to be a riboswitch. SAM-SAH ri...
SAM-SAH riboswitch - Wikipedia
Cyclic di-GMP-I riboswitch
Cyclic di-GMP-I riboswitches are a class of riboswitch that specifically bind cyclic di-GMP, which is a second messenger that is used in a variety of microbial processes including virulence, motility ...
Cyclic di-GMP-I riboswitch - Wikipedia
SAM riboswitch (S box leader)
The SAM riboswitch (also known as the S-box leader and now also called the SAM-I riboswitch) is found upstream of a number of genes which code for proteins involved in methionine or cysteine biosynthe...
SAM riboswitch (S box leader) - Wikipedia