Genome Editing with CRISPR-Cas9
This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Fen...
First Human Treated With CRISPR Gene-Edited Cells In China, Report Says
For the first time, a cancer patient is being treated with cells altered using a gene editing technique called CRISPR-Cas9.
Scientists Turn Bacteria Into Living Hard Drives
​Living organisms can store lines of code and pass them down to their progeny.​
CRISPR: Gene Editing Is Just The Beginning
The real power of the biological tool lies in exploring how genomes work. Molecular biologists are riding a wave of new technologies made possible by CRISPR.
CRISPR-like ‘immune’ system discovered in giant virus
Mimivirus defence system might lead to new genome-editing tools
Ethicists Approve “3 Parent” Embryos To Stop Diseases, But Congressional Ban Remains
An elite panel of scientists and bioethicists offered guarded approval Wednesday of a novel form of genetic engineering that could prevent congenital diseases but would result in babies with genetic m...
CRISPR Gene Editing Successfully Stops Muscular Dystrophy In Living Mice
If used on humans, the treatment could save hundreds of lives per year
Brave New World Of "Gene Doping” Ahead, Scientists Warn At Conference
Worries about “designer babies” might obscure the threat of far more likely abuses from a fast-moving genetic engineering method, researchers warned Tuesday at an international scientific summit. An e...
The Quest To Make CRISPR Even More Precise
To fulfill its revolutionary promise, the gene-editing technique will need to be edited. More than ever, we can view the genomes of humans and other organisms as drafts—not final and canonical texts, ...
Historic Summit On Gene Editing And ‘Designer Babies’ Convenes In Washington
Hundreds of scientists, policymakers and the president's science adviser have gathered Tuesday in Washington for what will be a three-day summit on genetic engineering, with a focus on a new, relative...
A Metabolic Master Switch Underlying Human Obesity Discovered
Obesity is one of the biggest public health challenges of the 21st century. Affecting more than 500 million people worldwide, obesity costs at least $200 billion each year in the United States alone, ...
In CRISPR Advance, Scientists Successfully Edit Human T Cells
In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9. Because th...
Massachusetts General Research Team Evolves CRISPR-Cas9 Nucleases With Novel Properties
A team of Massachusetts General Hospital researchers has found a way to expand the use and precision of the powerful gene-editing tools called CRISPR-Cas9 RNA-guided nucleases. In their report receivi...
Researchers Edit Plant DNA Using Mechanism Evolved In Bacteria
Researchers at the Univ. of Georgia have used a gene-editing tool known as CRISPR/Cas to modify the genome of a tree species for the first time. Their research, published online in New Phytologist, op...
MIT And UC Berkeley Dispute Over Rights To Gene Editing Tech
When gene editing came into the minds of scientists such technology was still regarded as sci fi stuff by most of the researchers in the academic communities. Nowadays, MIT and UC Berkeley dispute ove...
Telomere
A telomere is a region of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighbouring chromosomes. Its name...
Telomere - Wikipedia
CRISPR
CRISPRs (clustered regularly interspaced short palindromic repeats) are DNA loci containing short repetitions of base sequences. Each repetition is followed by short segments of "spacer DNA" from prev...
CRISPR - Wikipedia
Telomere-binding protein
Telomere-binding proteins are proteins that mediate telomere function by binding to them. There are two types of telomere-binding proteins: single-strand DNA telomere binding proteins and double-stra...
Microsatellite
Microsatellites, also known as simple sequence repeats (SSRs) or short tandem repeats (STRs), are repeating sequences of 2-5 base pairs of DNA. It is a type of Variable Number Tandem Repeat (VNTR).Mi...
Microsatellite - Wikipedia
JTB (gene)
Protein JTB, also known as the jumping translocation breakpoint protein or prostate androgen-regulated protein (PAR), is a protein that in humans is encoded by the JTB gene.The JTB family of proteins ...
JTB (gene) - Wikipedia
D-loop
In molecular biology, a displacement loop or D-loop is a DNA structure where the two strands of a double-stranded DNA molecule are separated for a stretch and held apart by a third strand of DNA. The...
D-loop - Wikipedia
Snpstr
A SNPSTR is a compound genetic marker composed of one or more SNPs and one microsatellite (STR). SNPSTRs were first described by Mountain et al. (2002) who developed experimental protocols for autosom...
Polymorphic simple sequence repeats database
PSSRdb (Polymorphic Simple Sequence Repeats database) is a database of polymorphic simple sequence repeats
Multiple Loci VNTR Analysis
Multiple Loci VNTR Analysis (MLVA ) is a method employed for the genetic analysis of particular microorganisms, such as pathogenic bacteria, that takes advantage of the polymorphism of tandemly repeat...
Chromatin bridge
Chromatin bridge is a mitotic occurrence that forms when telomeres of sister chromatids fuse together and fail to completely segregate into their respective daughter cells. Because this event is most ...
Chromatin bridge - Wikipedia
Cajal body
Cajal bodies (CBs) are spherical sub-organelles of 0.3-1.0 µm in diameter found in the nucleus of proliferative cells like embryonic cells and tumor cells, or metabolically active cells like neur...
Cajal body - Wikipedia
MICdb
MICdb (Microsatellites database) is a database of non-redundant microsatellites from prokaryotic genomes.